Eqvalan & Eqvalan Duo

Disclaimer: This site has been created by www.MedicAnimal.com for information purposes only. MedicAnimal is a proud retailer of Eqvalan & Eqvalan Duo but is not affiliated with or related to the manufacturer of Eqvalan & Eqvalan Duo and the contents of this site are neither sponsored or endorsed by the manufacturer of Eqvalan & Eqvalan Duo.

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Introduction

1. Eqvalan Oral Paste

2. Eqvalan Duo

Presentation

1. Eqvalan Oral Paste

A white ready-to-use paste formulation for oral administration containing 1.87% w/w ivermectin.

2. Eqvalan Duo

Oral paste containing: 1.55% w/w ivermectin and 7.75% w/w praziquantel.

Uses

1. Eqvalan Oral Paste

For the treatment and control of adult and immature roundworms, lungworms and bots of horses and donkeys.
EQVALAN Paste for Horses at the recommended dose rate of 200 micrograms ivermectin per kg bodyweight provides effective treatment and control of the following parasites of horses and donkeys:
Large strongyles
Strongylus vulgaris (adults and arterial larval stages), S. edentatus (adults and tissue larval stages), S. equinus (adults), Triodontophorus spp. (adults), T. brevicauda, T. serratus, Craterostomum acuticaudatum (adults).
Small strongyles
Adult and immature (fourth stage larvae) small strongyles or cyathostomes, including benzimidazole-resistant strains: Coronocyclus spp., including C. coronatus, C. labiatus, C. labratus; Cyathostomum spp., including C. catinatum, C. pateratum; Cylicocyclus spp., including C. ashworthi, C. elongatus, C. insigne, C. lepostomum, C. nassatus, C. radiatus; Cylicostephanus spp., including C. asymetricus, C. bidentatus, C. calicatus, C. goldi, C. longibursatus, C. minutus; Cylicodontophorus spp., including C. bicornatus; Gyalocephalus capitatus; Parapoteriostomum spp. including P. euproctus, P. mettami; Petrovinema spp. including P. poculatum; Poteriostomum spp. including P. imparidentatum.
Lungworms (adults and immatures)
Dictyocaulus arnfieldi
Pinworms (adults and immatures)
Oxyuris equi
Ascarids (adults and immature)
Parascaris equorum
Hairworms (adults)
Trichostrongylus axei
Large-mouth stomach worms (adults)
Habronema muscae
Neck threadworms (microfilariae)
Onchocerca spp.
Intestinal threadworms (adults)
Strongyloides westeri
Stomach bots
Oral and gastric stages of Gastrophilus spp.

 

2. Eqvalan Duo

For the treatment of mixed cestode (tapeworm) and nematode (roundworm) or arthropod (bot) infestations in horses.
The following parasites of horses are sensitive to the antiparasitic effects of EQVALAN DUO:
Tapeworms:
Anoplocephala perfoliata
Large strongyles:
Strongylus vulgaris (adults and arterial larval stages)
Strongylus edentatus (adults and tissue larval stages)
Strongylus equinus (adults)
Triodontophorus spp (adults)
Triodontophorus brevicauda
Triodontophorus serratus
Craterostomum acuticaudatum (adults)
Adult and immature (fourth-stage larvae) small strongyles or cyathostomes, including benzimidazole-resistant strains:
Coronocyclus spp
Coronocyclus coronatus
Coronocyclus labiatus
Coronocyclus labratus
Cyathostomum spp
Cyathostomum catinatum
Cyathostomum pateratum
Cylicocyclus spp
Cylicocyclus ashworthi
Cylicocyclus elongatus
Cylicocyclus insigne
Cylicocyclus leptostomum
Cylicocyclus nassatus
Cylicodontophorus spp
Cylicodontophorus bicornatus
Cylicostephanus spp
Cylicostephanus calicatus
Cylicostephanus goldi
Cylicostephanus longibursatus
Cylicostephanus minutus
Parapoteriostomum spp
Parapoteriostomum mettami
Petrovinema spp
Petrovinema poculatum
Poteriostomum spp
Adult hairworms: Trichostrongylus axei
Adult and immature pinworms: Oxyuris equi
Adult, third- and fourth-stage larvae of roundworms (ascarids): Parascaris equorum
Microfilariae of neck threadworms: Onchocerca spp
Adult intestinal threadworms: Strongyloides westeri
Adult large-mouth stomach worms: Habronema muscae
Oral and gastric stages of bots: Gasterophilus spp
Adult and immature lungworms: Dictyocaulus arnfieldi

 

Dosage & administration

1. Eqvalan Oral Paste

EQVALAN Paste for Horses is given orally at the recommended dose rate of 0.2 mg ivermectin per kg of bodyweight. Each syringe delivers 120 mg ivermectin, sufficient to treat 600 kg of bodyweight.
Parasitic control program
All horses and donkeys should be included in a regular parasite control program, with particular attention being paid to mares, foals and yearlings. Foals should be treated initially at 6 to 8 weeks of age, and routine treatment repeated as appropriate.
EQVALAN Paste for Horses is highly effective against gastro-intestinal, cutaneous and pulmonary nematodes and bots of horses. Regular treatment will reduce the chances of verminous arteritis and colic caused by Strongylus vulgaris. With its broad spectrum, the product is well suited to be the major medication in parasite control programs and is well suited to be the major component in a rotational program.
Dosing instructions
Each weight marking on the syringe plunger will deliver sufficient paste to treat 100kg bodyweight. Unlock the knurled ring by making ¼ turn and slide the knurled ring up the plunger shaft so that the side nearest the barrel is at the prescribed weight marking. Turn the knurled ring ¼ turn to lock in place. Remove the plastic cap from the tip of the nozzle. Make sure the horse's mouth contains no feed. Insert the syringe into the horse's mouth at the interdental space. Advance the plunger as far as it will go, depositing the medication on the base of the tongue.

 

2. Eqvalan Duo

The recommended dose is 200 mcg ivermectin per kg bodyweight and 1mg praziquantel per kg bodyweight (corresponding to 1.29g of paste per 100kg bodyweight in a single treatment).
Bodyweight and dosage should be accurately determined prior to treatment. The contents of one syringe will treat horses up to 600kg.
Calibrated markings are provided at 100kg bodyweight intervals. The syringe should be adjusted to the calculated dosage by setting the ring on the appropriate place on the plunger.
Parasite control program
Veterinary advice should be sought on appropriate dosing programs and stock management to achieve adequate parasite control for both tapeworm and roundworm infestations.
Dosing instructions
EQVALAN DUO oral paste is for oral administration only. While holding the plunger, turn the knurled ring on the plunger ¼ turn to the left and slide it so the stop ring is at the prescribed weight marking. Lock the ring in place by turning it ¼ turn to the right in order to bring the two arrows, the one visible on the ring and the one on the plunger rod, into alignment. Make sure the horse's mouth contains no feed. Remove the cover from the tip of the syringe. Insert the syringe tip into the horse’s mouth at the interdental space and deposit the paste on the base of the tongue. Immediately raise the horse’s head for a few seconds after dosing and ensure that the paste is consumed.

 

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Contra-indications, warnings, etc.

1. Eqvalan Oral Paste

Some horses carrying heavy infection of Onchocerca microfilariae have experienced oedema and pruritus following dosing, assumed to be the result of death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable.
EQVALAN Paste for Horses has been formulated specifically for use in horses and donkeys only. Dogs or cats may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes.
Do not smoke, eat or drink while handling the product. Wash hands after use.
This product may cause skin and eye irritation. Therefore, the user should avoid contact of the product with the skin and the eyes. In the case of contact rinse immediately with plenty of water.
In the case of accidental ingestion or eye irritation after contact seek medical advise immediately and show the package insert or the label to the physician.
For animal treatment only.
Withdrawal periods
Donkeys - meat: 21 days.
Horses - meat: 21 days.
Container disposal
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate ponds, waterways or ditches with the product or used container. Any unused veterinary medicinal product or waste material derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

 

2. Eqvalan Duo

Safety studies were not conducted in foals younger than 2 months of age, nor in stallions, therefore EQVALAN DUO cannot be recommended for use in these categories of animals.
The use of EQVALAN DUO may be dangerous to aquatic life. Horses should not have direct access to surface waters and ditches during treatment.
EQVALAN DUO has been formulated for use in horses only. Cats, dogs, especially Collies, Old English Sheepdogs and related breeds or crosses, and also turtles and tortoises may be adversely affected by the concentration of ivermectin in this product if they are allowed to ingest spilled paste or have access to used syringes.
Parasite resistance to any particular class of anthelmintic may develop following frequent, repeated use of an anthelmintic of that class.
Some horses with heavy infections of Onchocerca spp. microfilariae have experienced oedema and pruritus following treatment, assumed to be the result of the death of large numbers of microfilariae. These signs resolve within a few days but symptomatic treatment may be advisable. In cases of heavy infestations with tapeworms, signs of mild, transient colic and diarrhoea may be observed. There have been rare reports of swelling and irritation of the mouth, lip and tongue, and of salivation following administration of EQVALAN DUO. These reactions have been transitory in nature, appearing within 1 hour and abating within 24-48 hours following administration.
No undesirable effects related to treatment were observed in 2 month old horses treated with EQVALAN DUO at up to three times the recommended dose and in adult horses treated at ten times the recommended dose. Transient decreased food consumption, increased body temperature and impairment of vision were noticed in horses treated twice with an ivermectin oral paste at ten times the recommended dose (i.e., 2 mg/kg b.w.). All changes disappeared within five days. No antidote has been identified; however, symptomatic therapy may be beneficial.
User warnings
Wash hands after use.
Do not smoke, eat or drink while handling the product.
For animal treatment only.
This product may cause skin and eye irritation. Therefore, the user should avoid contact of the product with the skin and eyes. In case of contact, rinse immediately with plenty of water.
In the case of accidental ingestion or eye irritation after contact seek medical advice immediately and show the package leaflet or the label to the physician.
Use during pregnancy and lactation
Ivermectin-Praziquantel combination can be used after the first three months of gestation and during lactation. In the absence of clinical data in early pregnancy EQVALAN DUO can only be used in the first three months of gestation according to a risk benefit analysis by the veterinarian.
Withdrawal periods
Meat: 30 days. Do not use in mares producing milk for human consumption.
Container disposal
EXTREMELY DANGEROUS FOR FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used syringes. Dispose of any unused product and empty syringes in accordance with guidance from your local waste regulation authority.

 

Pharmaceutical precautions

1. Eqvalan Oral Paste

Do not store above 25°C.
Protect from light.
Keep out of the reach of children.

2. Eqvalan Duo

Keep out of the reach of children.
Store in the original container. Replace the cap after use. Part used syringes can be kept for up to 2 years after first use but should be used by the expiry date printed on the packaging.

 

Packaging quantities

1. Eqvalan Oral Paste

10 x 1 syringes each containing 6.42 g of 1.87% w/w ivermectin paste.

2. Eqvalan Duo

EQVALAN DUO is available in individual syringes containing 7.74 g of paste.

Further information

1. Eqvalan Oral Paste

Horses and donkeys of all ages, including young foals, pregnant mares and breeding stallions, have been treated with no adverse effects on their health and fertility.
EQVALAN Paste for Horses has been used in conjunction with other equine health care products and no interactions have been identified.
Mild transitory signs (slowed papillary light response and depression) have been seen at a dose of 1.8 mg/kg (9 times the recommended dose). Other signs seen at higher doses include mydriasis, ataxia, tremors, stupor, coma and death. The less severe signs have been transitory. No antidote has been identified; however, symptomatic therapy may be beneficial.

2. Eqvalan Duo

None.

Disclaimer

This site has been created by www.MedicAnimal.com for information purposes only. MedicAnimal is a proud retailer of Eqvalan & Eqvalan Duo but is not affiliated with or related to the manufacturer of Eqvalan & Eqvalan Duo and the contents of this site are neither sponsored or endorsed by the manufacturer of Eqvalan & Eqvalan Duo.